Pet Health

Equine Protozoal Myeloencephalitis (EPM) in Horses

Discover essential insights about Equine Protozoal Myeloencephalitis (EPM) in horses, including symptoms, diagnosis, and treatment options to ensure your horse's health.
Author: Veterinary Team
Dial A Vet
Updated
June 6, 2025
|
Published
June 6, 2025
A horse with neurological symptoms, showing signs of EPM, in a veterinary setting for diagnosis and treatment.

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Equine Protozoal Myeloencephalitis (EPM) can be a scary diagnosis for horse owners. This neurological disease, caused by a protozoal infection, can affect your horse's coordination, strength, and overall quality of life. The good news? With prompt recognition and treatment, many horses can recover and return to their usual activities. Let’s break down what EPM is, how to recognize it, and what you can do to help your horse.

⚠️ What to Watch For

Spotting EPM early can make a big difference in your horse’s recovery. Since it affects the central nervous system, symptoms can vary widely and may look like other conditions. Here are some signs to keep an eye out for:

  • Muscle atrophy, especially in the hindquarters
  • Uncoordinated or "wobbly" movement (ataxia)
  • Weakness or difficulty standing
  • Head tilt or facial nerve paralysis
  • Abnormal sweating
  • Seizures or collapse (in severe cases)

Symptoms often appear asymmetrically, meaning one side of the body may be more affected than the other. This unique characteristic can be a clue that your horse might have EPM.

🔍 Possible Causes

EPM is caused by a protozoan parasite, most commonly Sarcocystis neurona, and occasionally Neospora hughesi. These parasites are typically spread through the feces of opossums, which contaminate feed, water, or pasture. Horses become infected by ingesting these contaminated materials.

However, not every horse exposed to the parasite develops EPM. Factors like stress, poor nutrition, or an already weakened immune system can make some horses more vulnerable to the disease.

✅ What You Can Do at Home

While a veterinarian’s diagnosis and treatment are essential for EPM, there are steps you can take to support your horse and reduce the risk of infection:

  • Prevent opossums and other wildlife from accessing feed, water, and hay storage areas.
  • Regularly clean and sanitize feeding and watering equipment.
  • Maintain a clean and dry environment to minimize exposure to contaminated materials.
  • Feed high-quality, uncontaminated hay and grains.
  • Monitor your horse’s behavior and physical condition for any early signs of neurological issues.

If you suspect EPM, contact your veterinarian right away. Early intervention can significantly improve the chances of recovery.

💡 When to Call a Vet

Because EPM symptoms can mimic other neurological or musculoskeletal conditions, it’s crucial to have your horse evaluated by a veterinarian for an accurate diagnosis. Call your vet immediately if you notice:

  • Sudden or progressive loss of coordination
  • Muscle wasting that cannot be explained by other causes
  • Any signs of paralysis or difficulty moving

Your vet will likely perform a neurological exam and may recommend diagnostic tests such as blood or cerebrospinal fluid analysis to confirm EPM. Treatment often involves antiprotozoal medications, anti-inflammatory drugs, and supportive care tailored to your horse's specific needs.

FAQs

Q: Can EPM be cured?
A: While there is no guaranteed “cure” for EPM, many horses respond well to treatment with antiprotozoal medications. Early detection and consistent care improve the likelihood of recovery.

Q: Is EPM contagious to other horses?
A: No, EPM is not directly contagious between horses. The disease is spread through ingestion of feed or water contaminated with protozoa from opossum feces.

Q: How can I prevent EPM?
A: Prevention focuses on minimizing your horse’s exposure to opossum feces. Secure feed storage, clean water sources, and regular barn maintenance are key steps.

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References

While every effort is made to ensure the accuracy of this content - including vet review where applicable - this article is for informational purposes only and is not a substitute for professional veterinary advice, diagnosis, or treatment. If your pet is unwell or you are concerned, please speak with a licensed veterinarian. You can book a $49 online consultation with our veterinary team  😄
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